Clinical study results

  • The efficacy of the meridol® HALITOSIS mouthrinse on the reduction of oral malodour was compared with two commercially available CHX-containing mouthrinses (benchmark: 0.05% chlorhexidine (CHX), 0.05% cetylpyridinium chloride (CPC), 0.14% zinc lactate; positive control: 0.12% CHX) and tap water as negative control.
  • At baseline the participants showed elevated levels both in organoleptic and VSC values. They rinsed with 15 ml for 60 seconds twice daily after toothbrushing.
  • The malodour reduction of morning breath was assessed at baseline, days 1, 7 and 21 by trained sniffers using an organoleptic scale. Additionally, the total VSC concentration was determined.
  • meridol® HALITOSIS mouthrinse led to a significant reduction of organoleptic values compared to negative control. The effect was seen overnight (day 1) and was stable during the whole study.