Clinical study results

  • In this randomised, double-blind parallel trial inclusion criteria were an organoleptic score ≥ 2 and a H2S concentration in breath of more than 50 ppb.
  • Participants (n = 219) brushed their teeth twice a day for two minutes using an experimental tooth & tongue gel (1400 ppm F- from amine fluoride/stannous fluoride, 0.2% zinc lactate, oral malodour counteractives) or a control toothpaste (1400 ppm F- from sodium monofluorophosphate, without antimalodour ingredients). No additional oral hygiene was allowed. On the morning of readings participants refrained from oral hygiene, eating and drinking before readings.
  • The volatile sulphur compounds (VSC, main contributors to bad breath) were determined by OralChroma® device. VSC readings of morning breath were assessed at baseline, days 1, 7, 14 and 21.

Both test and control groups showed a significant decrease of VSC readings over time compared to baseline values. Additionally the application of the experimental tooth and tongue gel resulted in significantly lower VSC readings compared to control at all points of measurement.


An experimental tooth & tongue gel containing amine fluoride/stannous fluoride (1400 ppm F-), zinc lactate (0.2%) and oral malodour counteractives is effective in reducing malodorous substances in breath air. Application results in significantly lower VSC readings compared to control at all points of measurement.